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福尔马林固定与抗中性粒细胞胞浆抗体模式

Formalin fixation and patterns of antineutrophil cytoplasmic antibodies.

作者信息

Spickett G P, Broomhead V

机构信息

Regional Immunology Laboratory, Newcastle General Hospital, Newcastle upon Tyne.

出版信息

J Clin Pathol. 1995 Jan;48(1):89-90. doi: 10.1136/jcp.48.1.89.

Abstract

Recent publications have suggested that fixing neutrophils in formalin is a useful adjunct to the differentiation of antinuclear antibodies from perinuclear antineutrophil cytoplasmic antibodies. In this small comparative study of 30 sera the use of an additional slide of formalin fixed neutrophils did not add any useful information and may be confusing as the results were not reproducible.

摘要

近期的出版物表明,用福尔马林固定中性粒细胞有助于区分抗核抗体和核周型抗中性粒细胞胞浆抗体。在这项针对30份血清的小型对比研究中,使用额外一张福尔马林固定中性粒细胞的玻片并未提供任何有用信息,而且结果不可重复,可能会造成混淆。

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