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福尔马林固定与抗中性粒细胞胞浆抗体模式

Formalin fixation and patterns of antineutrophil cytoplasmic antibodies.

作者信息

Spickett G P, Broomhead V

机构信息

Regional Immunology Laboratory, Newcastle General Hospital, Newcastle upon Tyne.

出版信息

J Clin Pathol. 1995 Jan;48(1):89-90. doi: 10.1136/jcp.48.1.89.

DOI:10.1136/jcp.48.1.89
PMID:7706530
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC502272/
Abstract

Recent publications have suggested that fixing neutrophils in formalin is a useful adjunct to the differentiation of antinuclear antibodies from perinuclear antineutrophil cytoplasmic antibodies. In this small comparative study of 30 sera the use of an additional slide of formalin fixed neutrophils did not add any useful information and may be confusing as the results were not reproducible.

摘要

近期的出版物表明，用福尔马林固定中性粒细胞有助于区分抗核抗体和核周型抗中性粒细胞胞浆抗体。在这项针对30份血清的小型对比研究中，使用额外一张福尔马林固定中性粒细胞的玻片并未提供任何有用信息，而且结果不可重复，可能会造成混淆。

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Formalin fixation and patterns of antineutrophil cytoplasmic antibodies.福尔马林固定与抗中性粒细胞胞浆抗体模式
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本文引用的文献

1
The value of indirect immunofluorescence and solid phase techniques for ANCA detection. A report on the first phase of an international cooperative study on the standardization of ANCA assays. EEC/BCR Group for ANCA Assay Standardization.间接免疫荧光法和固相技术在抗中性粒细胞胞浆抗体（ANCA）检测中的价值。抗中性粒细胞胞浆抗体检测标准化国际合作研究第一阶段报告。欧洲经济共同体/生物技术协调行动组织抗中性粒细胞胞浆抗体检测标准化小组
J Immunol Methods. 1993 Feb 26;159(1-2):1-16. doi: 10.1016/0022-1759(93)90136-u.
2
ANCA and associated diseases: immunodiagnostic and pathogenetic aspects.抗中性粒细胞胞浆抗体及相关疾病：免疫诊断与发病机制方面
Clin Exp Immunol. 1993 Jan;91(1):1-12. doi: 10.1111/j.1365-2249.1993.tb03345.x.
3
ACP Broadsheet No 143: January 1994. Detection of autoantibodies to neutrophil cytoplasmic antigens.《内科学年鉴》简讯第143期：1994年1月。中性粒细胞胞浆抗原自身抗体的检测
J Clin Pathol. 1994 Jan;47(1):4-8. doi: 10.1136/jcp.47.1.4.
4
Delineation of a standard procedure for indirect immunofluorescence detection of ANCA.抗中性粒细胞胞浆抗体间接免疫荧光检测标准程序的描述。
APMIS Suppl. 1989;6:12-3.
5
Distinction between antinuclear antibody and P-ANCA.
J Clin Pathol. 1991 Nov;44(11):962-3. doi: 10.1136/jcp.44.11.962.