Sawabe K, Makiya K
Department of Parasitology and Tropical Public Health, University of Occupational and Environmental Health, Kitakyushu, Japan.
J Parasitol. 1995 Apr;81(2):228-33.
Angiostrongylus malaysiensis was isolated from wild rats Rattus norvegicus in a seaport area of Kitakyushu City, Kyushu, Japan in 1990. The infectivity and survival capacities of first-stage larvae of A. malaysiensis and Angiostrongylus cantonensis were compared under various conditions. Infectivity of first-stage larvae of the former in Biomphalaria glabrata was much lower than that of the latter. In an exposure at various pHs, and with various proteases and tissue homogenates of B. glabrata, the survival of first-stage larvae of A. malaysiensis was also lower than that of A. cantonensis. This lower survival was compared to that of A. cantonensis in response to desiccation of rat feces and high water temperature. First-stage larvae of A. malaysiensis thus appear to be influenced by conditions in the host's feces, specifically temperature and desiccation, and also show a greater sensitivity to pH and component proteases in the snail body than A. cantonensis.
1990年，在日本九州北九州市的一个海港地区，从野生褐家鼠体内分离出了马来西亚管圆线虫。在各种条件下比较了马来西亚管圆线虫和广州管圆线虫一期幼虫的感染力和生存能力。前者一期幼虫在光滑双脐螺体内的感染力远低于后者。在不同pH值环境下，以及接触光滑双脐螺的各种蛋白酶和组织匀浆时，马来西亚管圆线虫一期幼虫的存活率也低于广州管圆线虫。将这种较低的存活率与广州管圆线虫在大鼠粪便干燥和水温较高情况下的存活率进行了比较。因此，马来西亚管圆线虫一期幼虫似乎受宿主粪便中的条件影响，特别是温度和干燥，并且与广州管圆线虫相比，对蜗牛体内的pH值和蛋白酶成分表现出更高的敏感性。
