Prevalence of malaria and its relationship to anemia, blood glucose levels, and serum somatomedin c (IGF-1) levels in the Solomon Islands.

As part of establishing effective methods for malaria control, the malaria-associated nutritional status was surveyed on Guadalcanal Island in the Solomon Islands in 1993. A total of 506 residents participated in this study. The slide positive rate for malaria was 54% (275/506) in all ages, with a high of 79% for children aged 4-6 years. Plasmodium falciparum was the most common species (52%), followed by P. vivax (29%). Splenomegaly in children from infants to age 15 was detected at the rate of 30% (104/343) by the palpation method. Body mass index was lower in Solomon Islanders than for the Japanese population up to 15 years old in both genders. Mean values for serum insulin-like growth factor-1 (IGF-1) were also lower in Solomon Islanders in children under 18 years old. The hemoglobin distribution curves were almost identical in the malaria-positive (P(+)) and -negative (P(-)) groups. The percentage of cases with less than 80 mg/dl of blood glucose and those with less than 50 ng/ml of IGF-1 were higher in the P(+) group than for the anti-malaria drug-untreated malaria-negative (P(-)D(-)) group. It is suggested that low blood glucose and low IGF-1 levels may have some relationship with the malaria infection.