Kirk J K
Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, North Carolina, USA.
Am Fam Physician. 1995 Apr;51(5):1175-82, 1185.
Many nutrients substantially interfere with pharmacotherapeutic goals. The presence of certain nutrients in the gastrointestinal tract affects the bioavailability and disposition of many oral medications. Drug-nutrient interactions can also have positive effects that result in increased drug absorption or reduced gastrointestinal irritation. Knowing the significant drug-nutrient interactions can help the clinician identify the nutrients to avoid with certain medications, as well as the therapeutic agents that should be administered with food. This information can be used to educate patients and optimize pharmacotherapy.
许多营养素会严重干扰药物治疗目标。胃肠道中某些营养素的存在会影响许多口服药物的生物利用度和处置。药物-营养素相互作用也可能产生积极影响，导致药物吸收增加或胃肠道刺激减轻。了解重要的药物-营养素相互作用有助于临床医生确定某些药物应避免的营养素，以及应与食物一起服用的治疗药物。这些信息可用于对患者进行教育并优化药物治疗。
