Schneider C M, Dennehy C A, Rodearmel S J, Hayward J R
Department of Kinesiology, University of Northern Colorado, Greeley.
Ann Emerg Med. 1995 Apr;25(4):520-4. doi: 10.1016/s0196-0644(95)70270-9.
Creatine phosphokinase (CPK) and creatine kinase-MB (CK-MB) have been used extensively as diagnostic markers for myocardial infarction and skeletal muscle injury. Many factors affect the variability of serum CPK and serum CK-MB activity, especially physical activity. We discuss the influence of physical activity on muscle and serum CPK and CK-MB. The effect of acute and chronic exercise on CPK and CK-MB activity emphasizes the need to use measurements of serum CPK and CK-MB with caution when evaluating and diagnosing acute myocardial infarctions and skeletal muscle injury.
肌酸磷酸激酶(CPK)和肌酸激酶同工酶MB(CK-MB)已被广泛用作心肌梗死和骨骼肌损伤的诊断标志物。许多因素会影响血清CPK和血清CK-MB活性的变异性,尤其是体力活动。我们讨论了体力活动对肌肉以及血清CPK和CK-MB的影响。急性和慢性运动对CPK和CK-MB活性的影响强调,在评估和诊断急性心肌梗死和骨骼肌损伤时,谨慎使用血清CPK和CK-MB的测量结果。