Burns R J, Connolly G E
Denver Wildlife Research Center, United States Department of Agriculture, Colorado 80225-0266.
Arch Environ Contam Toxicol. 1995 Feb;28(2):141-4. doi: 10.1007/BF00217608.
The toxicity of Compound 1080 (sodium fluoroacetate) livestock protection collars (LPCs) to sheep was investigated. Lambs wearing punctured LPCs were observed to determine dermal toxicity, sheep were fed hay treated with LPC solution to find a lethal concentration, hay treated with a lethal concentration was subjected to sun and simulated rain to assess weathering influences, and sheep were held on pasture treated with LPC solution to evaluate grazing effects. Five lambs that wore punctured LPCs for up to seven days showed no dermal erythema or edema, but three died after ingesting 1080 from LPCs. All sheep died after eating 1.0 kg of hay treated with 3.75 ml, or more, of 1.0% LPC solution. Weathering 1.0 kg of hay treated with 3.75 ml of LPC solution in the sun for up to 12 weeks, reduced, but did not eliminate, toxicity; one inch or more of simulated rain eliminated toxicity. Survival of sheep in 250 m2 pens containing 1.1 m2 of forage treated with different amounts of LPC solution depended on the treatment and amount of treated forage consumed. LPC solution poses no dermal toxicity or irritation to sheep, and toxic effects on sheep from LPC solution on hay and forage was variable and situation dependent. Under conditions of exaggerated hazard, sheep can be poisoned by ingesting LPC solution, but adverse effects from normal LPC use are rare.
对1080化合物（氟乙酸钠）家畜保护项圈（LPCs）对绵羊的毒性进行了研究。观察佩戴有刺破口的LPCs的羔羊以确定皮肤毒性，给绵羊喂食经LPC溶液处理的干草以找出致死浓度，将经致死浓度处理的干草置于阳光下和模拟降雨条件下以评估风化影响，并且将绵羊圈养在用LPC溶液处理过的牧场上以评估放牧效果。五只佩戴有刺破口的LPCs长达七天的羔羊未出现皮肤红斑或水肿，但有三只在从LPCs摄入1080后死亡。所有绵羊在食用1.0千克用3.75毫升或更多的1.0%LPC溶液处理过的干草后死亡。将1.0千克用3.75毫升LPC溶液处理过的干草在阳光下风化长达12周，毒性降低但未消除；一英寸或更多的模拟降雨可消除毒性。在含有1.1平方米用不同量LPC溶液处理过的草料的250平方米围栏中绵羊的存活情况取决于处理方式和所消耗的经处理草料的量。LPC溶液对绵羊无皮肤毒性或刺激性，LPC溶液对干草和草料上的绵羊的毒性作用是可变的且取决于具体情况。在危险程度被夸大的情况下，绵羊可能因摄入LPC溶液而中毒，但正常使用LPC产生的不良影响很少见。
