Fossi M C
Dipartimento di Biologia Ambientale, University of Siena, Italy.
Environ Health Perspect. 1994 Dec;102 Suppl 12(Suppl 12):49-54. doi: 10.1289/ehp.94102s1249.
The aim of this article is to attempt a concise review of the state of the art of the nondestructive biomarkers approach in vertebrates, establishing a consensus on the most useful and sensitive nondestructive biomarker techniques, and proposing research priorities for the development and validation of this promising methodology. The following topics are discussed: the advantages of the use of nondestructive strategies in biomonitoring programs and the research fields in which nondestructive biomarkers can be applied; the biological materials suitable for nondestructive biomarkers and residue analysis in vertebrates; which biomarkers lend themselves to noninvasive techniques; and the validation and implementation strategy of the nondestructive biomarker approach. Examples of applications of this methodology in the hazard assessment of endangered species are also presented.
本文旨在对脊椎动物非破坏性生物标志物方法的现状进行简要综述，就最有用和最敏感的非破坏性生物标志物技术达成共识，并为这一有前景的方法的开发和验证提出研究重点。讨论了以下主题：在生物监测计划中使用非破坏性策略的优势以及可应用非破坏性生物标志物的研究领域；适用于脊椎动物非破坏性生物标志物和残留分析的生物材料；哪些生物标志物适用于非侵入性技术；以及非破坏性生物标志物方法的验证和实施策略。还介绍了该方法在濒危物种危害评估中的应用实例。
