Collins A, Landgren B M
Department of Clinical Neuroscience, Karolinska Hospital, Stockholm, Sweden.
Maturitas. 1994 Dec;20(2-3):101-11. doi: 10.1016/0378-5122(94)90005-1.
The aim of the study was to examine reproductive health, use of estrogen, lifestyle, experience of menopausal symptoms and work-role related issues in a population-based sample of perimenopausal women.
All women aged 48 years and residing in the catchment area of the Karolinska Hospital were recruited through the Swedish population register. They received a questionnaire covering sociodemographic background, reproductive health and gynaecological characteristics, social and work role related issues as well as a symptom rating scale.
Seventy percent of the women returned the questionnaire. Of these, 73% were premenopausal, 21% were postmenopausal and 6% were perimenopausal. Hormone replacement therapy was used by 7.5% of the respondents and the rate of hysterectomy was 8.6%. Regular exercise was reported by 44.4%. Factor analysis of the symptom ratings yielded four independent dimensions: Negative Moods, Vasomotor symptoms, Decreased Sexual Desire and Well-being. Multiple regression analyses showed that only vasomotor symptoms were significantly related to menopausal status. Negative Mood and Reduced Sexual Interest were better explained by the presence of vasomotor symptoms and by reproductive health and lifestyle variables such as current or previous PMS, dysmenorrhea, smoking and lack of exercise.
Only vasomotor symptoms were significantly related to menopausal status. Psychosocial and lifestyle variables as well as past or current reproductive health are more important determinants of women's psychological well-being during transition to menopause than menopausal status.
本研究旨在调查以人群为基础的围绝经期女性样本中的生殖健康、雌激素使用情况、生活方式、更年期症状体验以及与工作角色相关的问题。
通过瑞典人口登记册招募所有年龄在48岁且居住在卡罗琳斯卡医院服务区域内的女性。她们收到一份涵盖社会人口学背景、生殖健康和妇科特征、与社会及工作角色相关问题的问卷以及一份症状评分量表。
70%的女性返还了问卷。其中，73%处于绝经前，21%处于绝经后，6%处于围绝经期。7.5%的受访者使用激素替代疗法，子宫切除率为8.6%。44.4%的人报告有规律运动。症状评分的因子分析得出四个独立维度：消极情绪、血管舒缩症状、性欲减退和幸福感。多元回归分析表明，只有血管舒缩症状与绝经状态显著相关。消极情绪和性兴趣降低更好地由血管舒缩症状的存在以及生殖健康和生活方式变量（如当前或既往的经前综合征、痛经、吸烟和缺乏运动）来解释。
只有血管舒缩症状与绝经状态显著相关。在向更年期过渡期间，心理社会和生活方式变量以及过去或当前的生殖健康比绝经状态更重要地决定女性的心理健康。
