D'Almeida V, Hipólide D C, da Silva-Fernandes M E
Department of Biochemistry, Escola Paulista de Medicina, São Paulo, Brasil.
Physiol Behav. 1995 Feb;57(2):385-7. doi: 10.1016/0031-9384(94)00234-v.
The activity of antioxidant enzymes was investigated in red blood cells of male and female Wistar rats 3-4 months of age. Superoxide dismutase (EC 1.15.1.1), catalase (EC 1.11.1.6), and glutathione peroxidase (EC 1.11.1.9) did not show any significant variation in the different phases of the estrous cycle. No differences were observed for the three enzymes related to the sex of young rats. The present data enable us to consider that sexual differences as well as the changes in estrous cycle do not interfere in erythrocyte antioxidant enzymatic defense of rats.
对3 - 4月龄的雄性和雌性Wistar大鼠红细胞中的抗氧化酶活性进行了研究。超氧化物歧化酶（EC 1.15.1.1）、过氧化氢酶（EC 1.11.1.6）和谷胱甘肽过氧化物酶（EC 1.11.1.9）在发情周期的不同阶段均未显示出任何显著变化。未观察到这三种酶在幼鼠性别方面存在差异。目前的数据使我们能够认为，性别差异以及发情周期的变化不会干扰大鼠红细胞的抗氧化酶防御。
