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健康志愿者运动诱发室上性心动过速的患病率及预后意义

Prevalence and prognostic significance of exercise-induced supraventricular tachycardia in apparently healthy volunteers.

作者信息

Maurer M S, Shefrin E A, Fleg J L

机构信息

Laboratory of Cardiovascular Science and Longitudinal Studies, National Institute on Aging, National Institutes of Health, Baltimore, Maryland 21224, USA.

出版信息

Am J Cardiol. 1995 Apr 15;75(12):788-92. doi: 10.1016/s0002-9149(99)80412-3.

Abstract

The prevalence, characteristics, and prognostic significance of supraventricular tachycardia (SVT) occurring during maximal treadmill exercise testing were examined in 843 male and 540 female asymptomatic volunteers aged 20 to 94 years from the Baltimore Longitudinal Study of Aging who underwent exercise testing a mean of 2.3 times between 1977 and 1991. Exercise-induced SVT occurred during at least 1 test in 51 men (6.0%) and 34 women (6.3%), p = NS for gender. The 85 subjects with exercise-induced SVT were significantly older than the 1,298 free from this arrhythmia (66.0 +/- 13.5 vs 49.7 +/- 18.0 years, respectively, p < 0.001). The prevalence of SVT increased with age in men (p < 0.001) but not in women. Ninety-eight percent of the 141 discrete episodes of exercise-induced SVT were paroxysmal SVT, with heart rates varying from 105 to 290 beats/min (mean 186.3 +/- 43.3); only 16% were > 10 beats in duration and only 4% of subjects were symptomatic. Nearly half (44%) of SVT episodes occurred at peak effort. Coronary risk factors, echocardiographic left atrial size (3.3 +/- 6.7 vs 3.3 +/- 0.6 cm), and the prevalence of exercise-induced ischemic ST-segment depression (11% vs 13%) were similar in 85 subjects with SVT and 170 control subjects matched for age and sex.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

在巴尔的摩纵向衰老研究中,对843名年龄在20至94岁之间的男性和540名女性无症状志愿者进行了研究,这些志愿者在1977年至1991年间平均接受了2.3次运动测试,旨在探究最大运动平板试验期间发生的室上性心动过速(SVT)的患病率、特征及预后意义。51名男性(6.0%)和34名女性(6.3%)在至少1次测试中出现运动诱发的SVT,性别差异无统计学意义(p = NS)。85名出现运动诱发SVT的受试者比1298名未出现这种心律失常的受试者年龄显著更大(分别为66.0±13.5岁和49.7±18.0岁,p < 0.001)。男性中SVT的患病率随年龄增加(p < 0.001),但女性中未增加。141次运动诱发的SVT离散发作中,98%为阵发性SVT,心率范围为105至290次/分钟(平均186.3±43.3);持续时间>10次心跳的仅占16%,仅有4%的受试者有症状。近一半(44%)的SVT发作发生在运动峰值时。85名有SVT的受试者和170名年龄及性别匹配的对照受试者在冠心病危险因素、超声心动图左心房大小(3.3±6.7 vs 3.3±0.6 cm)以及运动诱发的缺血性ST段压低的患病率(11% vs 13%)方面相似。(摘要截选至250词)

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