Khan A L, Ah-See A K, Crofts T J, Heys S D, Eremin O
Department of Surgery, University of Aberdeen Medical School, Foresterhill.
Ann R Coll Surg Engl. 1995 Jan;77(1):16-20.
This retrospective study has reviewed the surgical management of the septic complications of diverticular disease involving the left colon in 77 patients who presented between 1980 and 1992. Over this period, Hartmann's resection continued to be the predominant surgical procedure. The overall mortality and morbidity rates in the study period were 10% and 31%, respectively. However, a marked improvement in survival was recorded in the latter half of the study (17% vs 6%). The mortality from Hartmann's resection was also reduced substantially in the second half of the study (24% vs 7.5%). These improvements occurred despite having a higher number of poor-risk patients (APACHE II score) with more severe pathology (generalised peritonitis, 35% vs 50%; faecal peritonitis, 9% vs 25%) in the latter half. There was a significantly worse survival in patients who were over 70 years of age (P < 0.03), those who had a severe concomitant medical illness (P < 0.02), those who had a generalised peritonitis (P < 0.02), and in those patients who had an APACHE II score of over 11 (P < 0.05) (Fisher's exact test). There was no difference in outcome (morbidity, mortality) between the various grades of surgeon involved in performing the emergency surgical procedures.
这项回顾性研究回顾了1980年至1992年间就诊的77例左半结肠憩室病感染性并发症的手术治疗情况。在此期间,哈特曼切除术仍然是主要的外科手术。研究期间的总死亡率和发病率分别为10%和31%。然而,研究后半期的生存率有显著提高(17%对6%)。研究后半期哈特曼切除术的死亡率也大幅降低(24%对7.5%)。尽管后半期有更多高危患者(急性生理与慢性健康状况评分II)且病理情况更严重(弥漫性腹膜炎,35%对50%;粪性腹膜炎,9%对25%),但仍出现了这些改善。70岁以上患者(P<0.03)、伴有严重内科疾病的患者(P<0.02)、患有弥漫性腹膜炎的患者(P<0.02)以及急性生理与慢性健康状况评分II超过11分的患者(P<0.05)(Fisher精确检验)的生存率明显更差。参与急诊手术的不同级别外科医生在结局(发病率、死亡率)方面没有差异。