CRST综合征（皮肤钙质沉着、雷诺现象、指（趾）硬化和毛细血管扩张）与自身免疫性肝炎相关。
CRST syndrome (calcinosis cutis, Raynaud's phenomenon, sclerodactyly, and telangiectasia) associated with autoimmune hepatitis.
作者信息
Ishikawa M, Okada J, Shibuya A, Kondo H
机构信息
Division of Rheumatology and Infectious Disease, Kitasato University School of Medicine, Sagamihara.
出版信息
Intern Med. 1995 Jan;34(1):6-9. doi: 10.2169/internalmedicine.34.6.
A case of Raynaud's phenomenon, was complicated with autoimmune hepatitis (AIH) during the clinical course, and subsequently with gangrene of the fingertips caused by CRST syndrome (calcinosis cutis, Raynaud's phenomenon, sclerodactyly and telangiectasia). The presence of anticentromere antibodies is rare in AIH; to date, there has been only one report of a combination of AIH and CRST syndrome. This combination of the two diseases has been identified only in Japan.
1例雷诺现象患者在临床过程中并发自身免疫性肝炎（AIH），随后又出现由CRST综合征（皮肤钙质沉着、雷诺现象、指（趾）硬化和毛细血管扩张）导致的指尖坏疽。抗着丝点抗体在AIH中罕见；迄今为止，仅有1例AIH与CRST综合征合并存在的报道。这两种疾病的这种合并情况仅在日本被发现。
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