Gatagonova T M
Med Tr Prom Ekol. 1994(12):17-21.
The study covered peculiarities of lipid metabolism in workers engaged into lead production. Most the examinees showed reliable increase of total blood cholesterol, low and extremely low density lipoproteins cholesterol, triglycerides and atherogenic coefficient, combined with decreased high density lipoproteins cholesterol. Occupational factor was proved dominant in atherosclerosis formation in lead production workers. Those workers demonstrated also significant comedown of Apo A-1 amount, reliable increase of Apo B level and Apo B/Apo A-1 ratio.
该研究涵盖了从事铅生产的工人的脂质代谢特点。大多数受检者的总血胆固醇、低密度和极低密度脂蛋白胆固醇、甘油三酯以及致动脉粥样化系数均有可靠的升高,同时高密度脂蛋白胆固醇降低。职业因素被证明在铅生产工人动脉粥样硬化形成中占主导地位。这些工人的载脂蛋白A-1含量也显著下降,载脂蛋白B水平和载脂蛋白B/载脂蛋白A-1比值可靠升高。