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正常人类胎儿免疫球蛋白M水平的测定。

Determination of normal human fetal immunoglobulin M levels.

作者信息

Vick D J, Hogge W A, Normansell D E, Burkett B J, Harbert G M

机构信息

Department of Obstetrics & Gynecology, University of Virginia Health Sciences Center, Charlottesville.

出版信息

Clin Diagn Lab Immunol. 1995 Jan;2(1):115-7. doi: 10.1128/cdli.2.1.115-117.1995.

DOI:10.1128/cdli.2.1.115-117.1995
PMID:7719902
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC170110/
Abstract

Immunoglobulin M (IgM) levels were measured in 198 cord blood samples from 192 apparently normal pregnancies from 24 weeks of gestation to term. Simple linear regression analysis yielded a standard curve for IgM development during pregnancy showing a 0.5 mg/dl increase in IgM per week of gestation. This curve allows the comparison of fetal IgM levels from pregnancies considered to be at risk for intrauterine infection.

摘要

对192例妊娠24周直至足月的明显正常妊娠的198份脐血样本进行了免疫球蛋白M（IgM）水平检测。简单线性回归分析得出了孕期IgM发育的标准曲线，显示妊娠每周IgM增加0.5mg/dl。该曲线可用于比较被认为有宫内感染风险的妊娠中胎儿的IgM水平。

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本文引用的文献

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Prenatal diagnosis of cytomegalovirus (CMV) infection: a preliminary report.巨细胞病毒（CMV）感染的产前诊断：初步报告。
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Prenatal serological diagnosis of intrauterine cytomegalovirus infection.宫内巨细胞病毒感染的产前血清学诊断
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Development of gamma G, gamma A, gamma M, beta IC-beta IA, C 1 esterase inhibitor, ceruloplasmin, transferrin, hemopexin, haptoglobin, fibrinogen, plasminogen, alpha 1-antitrypsin, orosomucoid, beta-lipoprotein, alpha 2-macroglobulin, and prealbumin in the human conceptus.人类胚胎中γG、γA、γM、βIC-βIA、C1酯酶抑制剂、铜蓝蛋白、转铁蛋白、血红素结合蛋白、触珠蛋白、纤维蛋白原、纤溶酶原、α1-抗胰蛋白酶、类粘蛋白、β-脂蛋白、α2-巨球蛋白和前白蛋白的发育情况。
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Serum levels of immune globulins in health and disease: a survey.健康与疾病状态下血清免疫球蛋白水平：一项调查
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Development of the immune response.
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Prenatal detection of rubella-specific IgM in fetal sera.
Prenat Diagn. 1985 Jan-Feb;5(1):21-6. doi: 10.1002/pd.1970050105.
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Prenatal and postnatal production of IgM and IgA antibodies to rubella virus studied by antibody capture immunoassay.通过抗体捕获免疫测定法研究风疹病毒IgM和IgA抗体的产前和产后产生情况。
J Infect Dis. 1988 Jul;158(1):138-43. doi: 10.1093/infdis/158.1.138.
10
Prenatal management of 746 pregnancies at risk for congenital toxoplasmosis.746例先天性弓形虫病高危妊娠的产前管理
N Engl J Med. 1988 Feb 4;318(5):271-5. doi: 10.1056/NEJM198802043180502.