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[猪囊尾蚴病小鼠模型的建立]

[Establishment of mouse model for Cysticercosis cellulosae].

作者信息

Yang X, Xu H, Cao Z, Wang W

机构信息

Department of Parasitology, Sun Yat-Sen University of Medical Sciences.

出版信息

Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 1994;12(4):297-9.

PMID:7720207
Abstract

Sixty mice were inoculated intravenously with 200-400 Taenia solium eggs collected from the gravid proglottides of the adult worm expelled from a taeniasis patient after pumpkin seed and areca treatment. The mice were killed and dissected 2 months after inoculation, and were found infected with Cysticercus cellulosae. These living cysticerci in muscles and lungs were elliptic in shape with diameters of 0.3-0.6 cm. The scolex was equipped with two rows of hooks and four typical suckers. When the cysticerci were hatched in gastric juice and bile for two hours at 37 degrees C the scoleces evaginated voluntarily. The results of this study suggest that the mouse can be used as an animal model for Cysticercus cellulosae.

摘要

从接受南瓜籽和槟榔治疗后排出的绦虫病患者成虫的妊娠节片中收集200 - 400个猪带绦虫卵,给60只小鼠静脉接种。接种2个月后处死并解剖小鼠,发现其感染有猪囊尾蚴。这些肌肉和肺中的活囊尾蚴呈椭圆形,直径为0.3 - 0.6厘米。头节上有两排小钩和四个典型的吸盘。当囊尾蚴在37摄氏度的胃液和胆汁中孵化两小时后,头节会自动外翻。本研究结果表明,小鼠可作为猪囊尾蚴的动物模型。

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1
[Establishment of mouse model for Cysticercosis cellulosae].[猪囊尾蚴病小鼠模型的建立]
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Experimental studies on physiological and morphological aspects of Cysticercus cellulosae in pigs.猪囊尾蚴生理和形态学方面的实验研究。
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