Morton C A, Shuttleworth D, Douglas W S
Department of Dermatology, Monklands District General Hospital, Airdrie, Scotland.
J Am Acad Dermatol. 1995 May;32(5 Pt 2):894-7. doi: 10.1016/0190-9622(95)91556-7.
We report the cases of three patients with Crohn's disease in whom porokeratosis developed. Disseminated superficial actinic porokeratosis developed in two patients. In one of these patients, the skin lesions arose during an exacerbation of the bowel disease. In the third patient, who had congenital linear porokeratosis, the disseminated superficial form of the disorder developed during the first severe exacerbation of Crohn's disease. A family history of porokeratosis was present in one patient, but no relatives of any of these patients were known to have Crohn's disease. In all three patients, Crohn's disease was limited to the colon.
我们报告了3例克罗恩病患者并发汗孔角化症的病例。其中2例患者发生了播散性浅表性光化性汗孔角化症。在这2例患者中，有1例的皮肤损害出现在肠道疾病加重期。第3例患者患有先天性线状汗孔角化症，在克罗恩病首次严重发作期间出现了该疾病的播散性浅表型。1例患者有汗孔角化症家族史，但这些患者的亲属均无克罗恩病。所有3例患者的克罗恩病均局限于结肠。
