Bhutto A M, Taira K, Nagamine Y, Maruno M, Takamiyagi A, Nonaka S
Department of Dermatology, Faculty of Medicine, University of the Ryukyus, Okinawa, Japan.
J Dermatol. 1995 Feb;22(2):107-10. doi: 10.1111/j.1346-8138.1995.tb03352.x.
A young Japanese man developed localized trichorrhexis nodosa (LTN) of the scalp hair in the winter season. To investigate the roles of shampoo, severe sunlight exposure and/or mechanical injuries, we performed the following studies. Hair was collected from the patient and from a control. The study was performed in two steps. In the first step, hair was put into shampoo, rinsed with saline water, and then exposed to ultraviolet B (UVB) radiation once a day for one week. In the second step, the hair was similarly treated, but each shaft was bent gently with forceps before UVB exposure. Scanning electron microscopic studies revealed cuticular changes when the hair was treated only with shampoo and UVB. When it was treated with shampoo, UVB, and mechanical bending, the patient's hair developed longitudinal and transverse fractures of the hair shafts, while the control hair showed only partial damage to the hair shaft. On the basis on the above findings, we conclude that mechanical bending may damage the hair shaft.
一名年轻的日本男性在冬季出现了头皮毛发局限性结节性脆发症（LTN）。为了研究洗发水、强烈阳光照射和/或机械损伤的作用，我们进行了以下研究。从患者和对照者处采集毛发。研究分两步进行。第一步，将毛发放入洗发水中，用盐水冲洗，然后每天暴露于紫外线B（UVB）辐射下，持续一周。第二步，对毛发进行类似处理，但在UVB照射前用镊子轻轻弯曲每根发干。扫描电子显微镜研究显示，仅用洗发水和UVB处理毛发时会出现角质层变化。当用洗发水、UVB和机械弯曲处理时，患者的毛发出现了发干的纵向和横向断裂，而对照毛发仅显示发干有部分损伤。基于上述发现，我们得出结论，机械弯曲可能会损伤发干。
