恶性疟原虫二氢叶酸还原酶-胸苷酸合成酶基因中的点突变与乙胺嘧啶和环氯胍耐药性 - Suppr

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超能文献

Point mutations in the dihydrofolate reductase-thymidylate synthase gene and pyrimethamine and cycloguanil resistance in Plasmodium falciparum.

作者信息

Basco L K, Eldin de Pécoulas P, Wilson C M, Le Bras J, Mazabraud A

机构信息

Centre de Génétique Moléculaire, Centre National de la Recherche Scientifique, Gif-sur-Yvette, France.

出版信息

Mol Biochem Parasitol. 1995 Jan;69(1):135-8. doi: 10.1016/0166-6851(94)00207-4.

DOI:10.1016/0166-6851(94)00207-4

PMID:7723784

Abstract

摘要

相似文献

Point mutations in the dihydrofolate reductase-thymidylate synthase gene and pyrimethamine and cycloguanil resistance in Plasmodium falciparum.恶性疟原虫二氢叶酸还原酶-胸苷酸合成酶基因中的点突变与乙胺嘧啶和环氯胍耐药性

Mol Biochem Parasitol. 1995 Jan;69(1):135-8. doi: 10.1016/0166-6851(94)00207-4.

Molecular epidemiology of malaria in Yaounde, Cameroon. VI. Sequence variations in the Plasmodium falciparum dihydrofolate reductase-thymidylate synthase gene and in vitro resistance to pyrimethamine and cycloguanil.喀麦隆雅温得疟疾的分子流行病学。VI. 恶性疟原虫二氢叶酸还原酶-胸苷酸合成酶基因的序列变异及对乙胺嘧啶和环氯胍的体外抗性

Am J Trop Med Hyg. 2000 Feb;62(2):271-6. doi: 10.4269/ajtmh.2000.62.271.

Amino acids in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum involved in cycloguanil resistance differ from those involved in pyrimethamine resistance.恶性疟原虫二氢叶酸还原酶-胸苷酸合成酶基因中与环氯胍耐药相关的氨基酸不同于与乙胺嘧啶耐药相关的氨基酸。

Proc Natl Acad Sci U S A. 1990 Apr;87(8):3014-7. doi: 10.1073/pnas.87.8.3014.

Plasmodium falciparum: mutation pattern in the dihydrofolate reductase-thymidylate synthase genes of Vietnamese isolates, a novel mutation, and coexistence of two clones in a Thai patient.恶性疟原虫：越南分离株二氢叶酸还原酶-胸苷酸合成酶基因的突变模式、一种新突变以及一名泰国患者体内两个克隆的共存

Exp Parasitol. 1996 Oct;84(1):56-64. doi: 10.1006/expr.1996.0089.

Plasmodium falciparum: rapid detection of dihydrofolate reductase mutations that confer resistance to cycloguanil and pyrimethamine.恶性疟原虫：快速检测赋予对环氯胍和乙胺嘧啶耐药性的二氢叶酸还原酶突变

Exp Parasitol. 1992 Jun;74(4):470-2. doi: 10.1016/0014-4894(92)90209-s.

[Gene point mutation in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum].[恶性疟原虫二氢叶酸还原酶-胸苷酸合成酶基因中的基因点突变]

Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2001;19(2):87-9.

Molecular basis of differential resistance to cycloguanil and pyrimethamine in Plasmodium falciparum malaria.恶性疟原虫对环氯胍和乙胺嘧啶耐药性差异的分子基础

Proc Natl Acad Sci U S A. 1990 Apr;87(8):3018-22. doi: 10.1073/pnas.87.8.3018.

Point mutations in the dihydrofolate reductase and dihydropteroate synthetase genes and in vitro susceptibility to pyrimethamine and cycloguanil of Plasmodium falciparum isolates from Papua New Guinea.来自巴布亚新几内亚的恶性疟原虫分离株二氢叶酸还原酶和二氢蝶酸合酶基因中的点突变以及对乙胺嘧啶和环氯胍的体外敏感性

Am J Trop Med Hyg. 1996 Aug;55(2):209-13. doi: 10.4269/ajtmh.1996.55.209.

Molecular epidemiology of malaria in Yaounde, Cameroon I. Analysis of point mutations in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum.喀麦隆雅温得疟疾的分子流行病学 I. 恶性疟原虫二氢叶酸还原酶-胸苷酸合成酶基因点突变分析

Am J Trop Med Hyg. 1998 Mar;58(3):369-73. doi: 10.4269/ajtmh.1998.58.369.

[In vitro sensitivity of Plasmodium falciparum to anti-folinic agents (trimethoprim, pyrimethamine, cycloguanil): a study of 29 African strains].恶性疟原虫对抗亚叶酸剂（甲氧苄啶、乙胺嘧啶、环氯胍）的体外敏感性：对29株非洲菌株的研究

Bull Soc Pathol Exot. 1997;90(2):90-3.

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