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一名患艾滋病儿童中与慢性卡氏肺孢子虫感染相关的严重囊性肺部疾病。

Severe cystic pulmonary disease associated with chronic Pneumocystis carinii infection in a child with AIDS.

作者信息

Evlogias N E, Leonidas J C, Rooney J, Valderama E

机构信息

Department of Radiology, Schneider Children's Hospital, New Hyde Park, NY 11040, USA.

出版信息

Pediatr Radiol. 1994;24(8):606-8. doi: 10.1007/BF02012749.

DOI:10.1007/BF02012749
PMID:7724292
Abstract

A 3-year-old HIV-positive boy developed Pneumocystis carinii pneumonia (PCP) resulting in chronic interstitial pulmonary disease, which persisted for the following 3 years; he was essentially asymptomatic and the lung findings had therefore been attributed to lymphocytic interstitial pneumonia (LIP). He subsequently developed extensive cystic pulmonary disease, documented by CT, leading to recurrent pneumothorax and severe pulmonary insufficiency. Lung biopsy revealed chronic PCP infection associated with extensive pulmonary fibrosis and calcification. This case suggests that Pneumocystis carinii may cause chronic progressive pulmonary fibrosis with cyst formation and respiratory failure.

摘要

一名3岁的HIV阳性男孩患上了卡氏肺孢子虫肺炎(PCP),导致慢性间质性肺病,该病在接下来的3年里持续存在;他基本没有症状,因此肺部表现一直被归因于淋巴细胞间质性肺炎(LIP)。他随后出现了广泛的囊性肺病,CT检查证实了这一点,导致反复气胸和严重的肺功能不全。肺活检显示慢性PCP感染伴有广泛的肺纤维化和钙化。该病例表明,卡氏肺孢子虫可能导致伴有囊肿形成和呼吸衰竭的慢性进行性肺纤维化。

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引用本文的文献

1
Pneumothorax as the presenting sign of Pneumocystis carinii infection in an HIV-positive child with prior lymphocytic interstitial pneumonitis.
Pediatr Radiol. 1996;26(8):559-62. doi: 10.1007/BF01372242.

本文引用的文献

1
Pediatric HIV infection in its second decade--the changing pattern of lung involvement. Clinical, plain film, and computed tomographic findings.儿童HIV感染进入第二个十年——肺部受累模式的变化。临床、X线平片及计算机断层扫描结果
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2
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与卡氏肺孢子虫肺炎相关的肺囊肿:影像学特征、自然病史及并发症
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Children with AIDS--is pathologic diagnosis possible based on chest radiographs?患有艾滋病的儿童——能否根据胸部X光片做出病理诊断?
Pediatr Radiol. 1987;17(4):303-7. doi: 10.1007/BF02388243.
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Roentgenographic patterns of Pneumocystis carinii pneumonia in 104 patients with AIDS.104例艾滋病患者卡氏肺孢子虫肺炎的X线表现
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Pulmonary disease in children with acquired immune deficiency syndrome and AIDS-related complex.获得性免疫缺陷综合征及艾滋病相关综合征患儿的肺部疾病
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Pulmonary cysts associated with Pneumocystis carinii pneumonia in patients with AIDS.艾滋病患者中与卡氏肺孢子虫肺炎相关的肺囊肿。
Radiology. 1989 Oct;173(1):33-5. doi: 10.1148/radiology.173.1.2789413.
10
Pulmonary cystic disease: comparison of Pneumocystis carinii pneumatoceles and bullous emphysema due to intravenous drug abuse.肺囊性疾病:卡氏肺孢子虫气囊肿与静脉药物滥用所致大疱性肺气肿的比较
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