Guhlmann C A, Rendl J, Börner W
Klinik und Poliklinik für Nuklearmedizin, Universität Würzburg.
Nuklearmedizin. 1995 Feb;34(1):20-3.
We studied the effects of radioiodine therapy (RIT) for autonomously functioning thyroid nodules (AFTNs) and Graves' disease on thyroid function and size up to one year after RIT. In 230 patients with AFTNs, a dose of 300 Gy was effective in about 90% of the cases 6 months after RIT. Out of 65 patients suffering from Graves' disease, 5 patients (8%) had persisting hyperthyroidism 6 months after RIT with a dose of 150 Gy. This group consisted exclusively of patients with manifest hyperthyroidism at the time of RIT. As determined by ultrasonography 6 months after RIT, a reduction of thyroid size by about 40% and 60% was observed in patients with AFTNs and Graves' disease, respectively.
我们研究了放射性碘治疗（RIT）对自主功能性甲状腺结节（AFTN）和格雷夫斯病患者甲状腺功能及大小的影响，随访时间长达RIT治疗后一年。在230例AFTN患者中，300 Gy的剂量在RIT治疗6个月后约90%的病例中有效。在65例格雷夫斯病患者中，5例（8%）在接受150 Gy剂量的RIT治疗6个月后仍存在甲状腺功能亢进。该组仅包括RIT治疗时表现为甲状腺功能亢进的患者。RIT治疗6个月后通过超声检查确定，AFTN和格雷夫斯病患者的甲状腺大小分别减少了约40%和60%。
