Finley R W, Cleary J D, Goolsby J, Chapman S W
Department of Medicine, University of Mississippi Medical Center, Jackson 39216, USA.
Antimicrob Agents Chemother. 1995 Feb;39(2):553-5. doi: 10.1128/AAC.39.2.553.
Fluconazole concentrations in the serum and prostate of human volunteers undergoing transurethral resection for benign prostatic hypertrophy were measured. There was a high correlation (r = 0.783) between serum (mean = 6.6 micrograms/ml) and tissue (mean = 1.9 micrograms/g) fluconazole concentrations, and these data were used to construct a model for local tissue concentrations.
对因良性前列腺增生接受经尿道切除术的人类志愿者的血清和前列腺中的氟康唑浓度进行了测量。血清(平均 = 6.6微克/毫升)和组织(平均 = 1.9微克/克)中的氟康唑浓度之间存在高度相关性(r = 0.783),并且这些数据被用于构建局部组织浓度模型。