Combined immunomodulation (Propionibacterium avidum KP-40) and lectin blocking (D-galactose) prevents liver tumor colonization in BALB/c-mice. - Suppr | 超能文献

Combined immunomodulation (Propionibacterium avidum KP-40) and lectin blocking (D-galactose) prevents liver tumor colonization in BALB/c-mice.

作者信息

Pulverer G, Ko H L, Tunggal L, Beuth J, Jeljaszewicz J

机构信息

Institute of Medical Microbiology and Hygiene, University of Cologne, FRG.

出版信息

Zentralbl Bakteriol. 1994 Nov;281(4):491-4. doi: 10.1016/s0934-8840(11)80336-1.

DOI:10.1016/s0934-8840(11)80336-1

Abstract

The protective effect of combined treatment (immunomodulation with Propionibacterium avidum KP-40; liver lectin blocking by D-galactose administration) on the liver colonization of RAW 117-H10 lymphosarcoma was investigated in BALB/c-mice. Both, immunomodulation with P. avidum KP-40 as well as liver lectin blocking by D-galactose treatment significantly decreased the number of liver tumor colonies in this experimental model. However, the combination of P. avidum KP-40 and D-galactose obviously proved to be superior to each monotherapy since the liver colonization by RAW 117-H 10 lymphosarcoma could be completely inhibited.

摘要

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