Rudenko A V, Kruglikov V T
Mikrobiol Z. 1995 Jan-Feb;57(1):102-10.
Various aspects of ionizing radiation action on microorganisms and course of endo- and exogenous infections are considered. The immune response is discussed from the standpoint of its significance in development of infectious-inflammatory processes under conditions of radiation of a microorganism and higher radiation background. Quantitative and functional changes in the immune system of the organism subjected to radiation are discussed in detail and peculiarities of these changes under low doses of radiation are shown. The analysis of the data obtained has confirmed a decrease of the natural resistance of organism to various infectious agents of endo- and exogenous origin under the effect of ionizing radiation; the main reason of that is disturbance of the immunity system, particularly at the cellular level.
本文探讨了电离辐射对微生物的作用以及内源性和外源性感染的发展过程的各个方面。从免疫反应在微生物辐射和更高辐射背景条件下感染性炎症过程发展中的意义的角度进行了讨论。详细讨论了受辐射生物体免疫系统的定量和功能变化，并展示了低剂量辐射下这些变化的特点。对所得数据的分析证实，在电离辐射的作用下，生物体对各种内源性和外源性感染因子的天然抵抗力下降；其主要原因是免疫系统受到干扰，特别是在细胞水平上。
