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[低剂量电离辐射暴露人群的非特异性抵抗力]

[Non-specific resistance in people exposed to low doses of ionizing radiation].

作者信息

Grishanin V A, Nikolaevich M S

出版信息

Med Tr Prom Ekol. 1993(9-10):23-6.

PMID:8087464
Abstract

Lysosomal cation test was applied to evaluation of nonspecific immune resistance in people exposed to small radiation doses. The surface dose over 5 mSv per year induced preservation or increase of cationic proteins. This state was not stable and later the concentration of cationic proteins tended to decrease. The subnormal granules were detected in the people exposed to radiation. The number of the granules depended on the level and time of exposure, so such subnormal granules can be considered a specific marker of radiation exposure. Prolonged simultaneous surface and interstitial radiation leads to the stable decrease of nonspecific immune resistance. Lysosomal cation test was proved to be one of the most acceptable methods for rapid mass evaluation of nonspecific immune resistance in people exposed to radiation.

摘要

溶酶体阳离子试验用于评估小剂量辐射暴露人群的非特异性免疫抵抗力。每年超过5毫希沃特的体表剂量会导致阳离子蛋白的保留或增加。这种状态并不稳定,随后阳离子蛋白的浓度趋于下降。在辐射暴露人群中检测到亚正常颗粒。颗粒数量取决于暴露水平和时间,因此这种亚正常颗粒可被视为辐射暴露的特异性标志物。长时间同时进行体表和间质辐射会导致非特异性免疫抵抗力持续下降。溶酶体阳离子试验被证明是快速大规模评估辐射暴露人群非特异性免疫抵抗力的最可接受方法之一。

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