Weisberg E
Family Planning NSW Ltd, Sydney, Australia.
Drugs. 1995 Feb;49(2):224-31. doi: 10.2165/00003495-199549020-00007.
The combined oral contraceptive pill is the most popular method of contraception worldwide, with modern low-dose formulations significantly improving tolerability. Breakthrough bleeding is the most significant adverse event associated with the low-dose combined oral contraceptives. Monophasic, biphasic, triphasic and progestogen-only preparations are available, and the choice of formulation should be tailored to best suit the patient. Any areas of uncertainty or concern that the patient has should be addressed, and the patient should be clearly informed of how to use the oral contraceptive effectively, the likely initial adverse effects and what to do if a pill is missed.
复方口服避孕药是全球最流行的避孕方法,现代低剂量配方显著提高了耐受性。突破性出血是与低剂量复方口服避孕药相关的最显著不良事件。有单相、双相、三相和仅含孕激素的制剂可供选择,制剂的选择应根据患者的具体情况进行调整以达到最佳适配。患者存在的任何不确定或担忧的方面都应得到解决,并且应明确告知患者如何有效使用口服避孕药、可能出现的初始不良反应以及漏服药物时该怎么办。