Tsolov Kh, Strezov S, Charukchiev D, Dimitrova G, Miladinova S
Probl Khig. 1977;3:47-60.
The clinical picture and treatment of exacerbated chronic respiratory insufficiency is studied in 189 silicosis patients with different stage and degree of decompensation. It is found out that chronic respiratory insufficiency determination in these patients is conditioned by the exacerbation of a chronic inflammtory process in the bronchi and lungs (68.2 per cent), or by intercurrent acute inflammtory pulmonary process (15.9 per cent). The clinical manifestation of the disease is aggravated and modified by the appearance of new clinical elements, resulting in the typical clinical picture of inflammatory decompensation of silicosis. It is stressed that the effect of treatment is greater, the milder the stage of the disease, and the earlier and less marked the decompensation-induced derangements. Lethality in patients with III degree silicosis amounts to 8,2 per cent, and in patients with III degree respiratory insufficiency -- to 30.7 per cent. A complex active therapy program for silicosis patients with exacerbated chronic respiratory insufficiency is proposed.
对189例处于不同失代偿期阶段和程度的矽肺患者慢性呼吸功能不全加重的临床表现及治疗进行了研究。结果发现，这些患者慢性呼吸功能不全的判定取决于支气管和肺部慢性炎症过程的加重（68.2%），或取决于并发的急性炎症性肺部病变（15.9%）。疾病的临床表现因新的临床症状出现而加重和改变，从而导致矽肺炎症性失代偿的典型临床表现。强调疾病阶段越轻、失代偿引起的紊乱出现越早且越不明显，治疗效果越好。Ⅲ期矽肺患者的死亡率为8.2%，Ⅲ度呼吸功能不全患者的死亡率为30.7%。提出了针对慢性呼吸功能不全加重的矽肺患者的综合积极治疗方案。
