在俄罗斯西北部及周边地区分离出的产毒素白喉棒状杆菌菌株对十种抗生素的体外敏感性

The in-vitro susceptibilities of toxigenic strains of Corynebacterium diphtheriae isolated in northwestern Russia and surrounding areas to ten antibiotics.

作者信息

Maple P A, Efstratiou A, Tseneva G, Rikushin Y, Deshevoi S, Jahkola M, Vuopio-Varkila J, George R C

机构信息

Respiratory and Systemic Infection Laboratory, Central Public Health Laboratory, Colindale, London, UK.

出版信息

J Antimicrob Chemother. 1994 Dec;34(6):1037-40. doi: 10.1093/jac/34.6.1037.

DOI:10.1093/jac/34.6.1037

PMID:7730218

Abstract

The in-vitro activities of ten antibiotics against 83 toxigenic strains of Corynebacterium diphtheriae recently isolated in northwestern Russia and surrounding areas were determined by an agar dilution method. All of the strains were susceptible to erythromycin, penicillin, ampicillin, cefuroxime, chloramphenicol, ciprofloxacin, gentamicin and tetracycline. Trimethoprim and rifampicin were each active against 81 isolates, the two strains resistant to the latter agent having been isolated from two members of the same family.

摘要

采用琼脂稀释法测定了10种抗生素对最近在俄罗斯西北部及周边地区分离出的83株产毒素白喉棒状杆菌的体外活性。所有菌株对红霉素、青霉素、氨苄西林、头孢呋辛、氯霉素、环丙沙星、庆大霉素和四环素均敏感。甲氧苄啶和利福平分别对81株菌株有活性，对后一种药物耐药的两株菌株来自同一家族的两名成员。