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替考拉宁与其他抗生素对JK类白喉杆菌的体外活性比较

Comparative in vitro activities of teichomycin and other antibiotics against JK diphtheroids.

作者信息

Jadeja L, Fainstein V, LeBlanc B, Bodey G P

出版信息

Antimicrob Agents Chemother. 1983 Aug;24(2):145-6. doi: 10.1128/AAC.24.2.145.

Abstract

The in vitro susceptibilities of 98 isolates of JK diphtheroids to teichomycin, vancomycin, and eight other antibiotics was investigated. Teichomycin and vancomycin were extremely active against all the isolates tested. The 90% minimal inhibitory concentrations for teichomycin and vancomycin were 1.56 and 0.78 micrograms/ml, respectively. The majority of the isolates were resistant to ticarcillin, methicillin, erythromycin, tetracycline, chloramphenicol, clindamycin, and cephalothin.

摘要

研究了98株JK类白喉杆菌对替考拉宁、万古霉素和其他8种抗生素的体外敏感性。替考拉宁和万古霉素对所有测试菌株都具有极高活性。替考拉宁和万古霉素的90%最小抑菌浓度分别为1.56微克/毫升和0.78微克/毫升。大多数菌株对替卡西林、甲氧西林、红霉素、四环素、氯霉素、克林霉素和头孢噻吩耐药。

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