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Induction of prostaglandin H synthase-2 in rat carrageenin-induced pleurisy and effect of a selective COX-2 inhibitor.

作者信息

Katori M, Harada Y, Hatanaka K, Majima M, Kawamura M, Ohno T, Aizawa A, Yamamoto S

机构信息

Department of Pharmacology, Kitasato University School of Medicine, Kanagawa, Japan.

出版信息

Adv Prostaglandin Thromboxane Leukot Res. 1995;23:345-7.

PMID:7732867
Abstract
摘要

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1
Induction of prostaglandin H synthase-2 in rat carrageenin-induced pleurisy and effect of a selective COX-2 inhibitor.角叉菜胶诱导的大鼠胸膜炎中前列腺素H合成酶-2的诱导及选择性COX-2抑制剂的作用
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Selective inhibition of cyclooxygenase-2 (COX-2) reduces prostaglandin E2 production and attenuates systemic disease sequelae in experimental pancreatitis.选择性抑制环氧化酶-2(COX-2)可减少前列腺素E2的产生,并减轻实验性胰腺炎中的全身疾病后遗症。
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引用本文的文献

1
Cyclooxygenase-2 and its regulation in inflammation.环氧化酶-2及其在炎症中的调节
Mediators Inflamm. 1996;5(5):305-23. doi: 10.1155/S0962935196000452.
2
Dissociation of spinal microglia morphological activation and peripheral inflammation in inflammatory pain models.炎症性疼痛模型中脊髓小胶质细胞形态激活与外周炎症的解离
J Neuroimmunol. 2007 Dec;192(1-2):40-8. doi: 10.1016/j.jneuroim.2007.09.003. Epub 2007 Oct 4.
3
The acute antihyperalgesic action of nonsteroidal, anti-inflammatory drugs and release of spinal prostaglandin E2 is mediated by the inhibition of constitutive spinal cyclooxygenase-2 (COX-2) but not COX-1.
非甾体抗炎药的急性抗痛觉过敏作用以及脊髓前列腺素E2的释放是由对组成型脊髓环氧化酶-2(COX-2)而非COX-1的抑制介导的。
J Neurosci. 2001 Aug 15;21(16):5847-53. doi: 10.1523/JNEUROSCI.21-16-05847.2001.
4
Increased migration of neutrophils to granulocyte-colony stimulating factor in rat carrageenin-induced pleurisy: roles of complement, bradykinin, and inducible cyclooxygenase-2.在大鼠角叉菜胶诱导的胸膜炎中,中性粒细胞向粒细胞集落刺激因子的迁移增加:补体、缓激肽和诱导型环氧化酶-2的作用
Inflamm Res. 1996 Jul;45(7):335-46. doi: 10.1007/BF02252946.