Ogurtsov R P
Biull Eksp Biol Med. 1975 Dec;80(12):59-62.
C. albicans vaccine was administered to newborn mice (CC57BR). A tolerance to the microbial antigen was thus obtained which depressed the reaction of rejection of the C3H mice skin allograft. Tolerant mice displayed a reduction of the number of lymphoid cells reacting with the microbial and tissue antigen of the donor in the reactions of immunoadhesion and blasttransformation; there was also seen a reduction of the cytotoxic activity to the fibroblasts of C3H mice. The tolerance to the microbial and cross reacting transplantation antigens was pased by the spleen cells to syngenous recipients irradiated in a dose of 700 R.
将白色念珠菌疫苗接种给新生小鼠（CC57BR）。由此获得了对微生物抗原的耐受性，这抑制了C3H小鼠皮肤同种异体移植的排斥反应。耐受小鼠在免疫粘附和胚细胞转化反应中，与供体微生物和组织抗原发生反应的淋巴细胞数量减少；对C3H小鼠成纤维细胞的细胞毒性活性也有所降低。对微生物和交叉反应移植抗原的耐受性通过脾细胞传递给接受700拉德剂量照射的同基因受体。
