Ashammakhi N, Mäkelä E A, Vihtonen K, Rokkanen P, Kuisma H, Törmälä P
Department of Orthopaedics and Traumatology, Helsinki University Central Hospital, Finland.
Biomaterials. 1995 Jan;16(2):135-8. doi: 10.1016/0142-9612(95)98276-k.
Self-reinforced polyglycolide (SR-PGA) devices are stronger than non-reinforced ones. To study the strength retention of SR-PGA membrane, in vitro and in vivo, membranes were either immersed in distilled water at 37 degrees C, or implanted in the subcutis or around the femoral bone of rats. The SR-PGA membranes lost their strength in vitro by 6 wk, while they retained it for 15 wk in vivo due to the fibrous tissue that formed around and inside the implant (biomembrane). This is an advantage when clinical application of the membrane is being considered.
自增强聚乙交酯（SR-PGA）装置比未增强的装置更强。为了研究SR-PGA膜在体外和体内的强度保持情况，将膜要么浸入37摄氏度的蒸馏水中，要么植入大鼠的皮下或股骨周围。SR-PGA膜在体外6周后失去强度，而在体内由于植入物（生物膜）周围和内部形成的纤维组织，其强度保持了15周。在考虑该膜的临床应用时，这是一个优势。
