Vasenius J, Vainionpää S, Vihtonen K, Mäkelä A, Rokkanen P, Mero M, Törmälä P
Department of Orthopaedics and Traumatology, University Central Hospital, Helsinki, Finland.
Biomaterials. 1990 Sep;11(7):501-4. doi: 10.1016/0142-9612(90)90065-x.
To evaluate the behaviour of mechanical properties of absorbable osteosynthesis implants in vivo, the strength retention of self-reinforced polyglycolide rods in distilled water at 37 degrees C in the subcutis and femoral medullary cavity of the rabbit was investigated. The self-reinforced polyglycolide rods lost their strength significantly faster in vivo than in vitro. The strength loss of the self-reinforced polyglycolide rods was only slightly faster in the medullary cavity than in the subcutis. As the removal of the implants from the medullary cavity became difficult 5-6 wk after implantation, it is suggested that subcutaneous implantation would be a suitable method to evaluate the strength retention of absorbable osteosynthesis implants.
为评估可吸收接骨植入物在体内的力学性能表现，研究了自制增强聚乙交酯棒在37℃蒸馏水中、兔皮下及股骨髓腔内的强度保持情况。自制增强聚乙交酯棒在体内的强度丧失明显快于体外。自制增强聚乙交酯棒在髓腔内的强度丧失仅比皮下稍快。由于植入后5-6周从髓腔取出植入物变得困难，建议皮下植入是评估可吸收接骨植入物强度保持的合适方法。
