Fernández Jorge M A, Alonso Mallo E
Unidad de Neumología, Hospital Río Carrión, Palencia.
An Med Interna. 1994 Dec;11(12):588-90.
We studied the seric activity of the angiotensin converting enzyme (ACE) in 19 patients with sarcoidosis, 14 tuberculosis, 16 silicosis and 15 workers of coal mining without silicosis and other concomitant diseases, in order to assess its usefulness as orientative parameter for the differential diagnosis of these processes. We found significantly increased values with respect to the control group in all of them: control group (40.84 +/- 13.06 U/l), sarcoidosis (57.77 +/- 16.47 U/l), tuberculosis (46.85 +/- 10.25 U/l), silicosis (61.50 +/- 21.40 U/l), miners (71.50 +/- 12.48 U/l). We did not detect any statistically significant differences between the several diagnostic groups except for miners and tuberculosis (p = 0.04). We conclude that this parameter is hot very useful for the diagnostic orientation of these processes.
我们研究了19例结节病患者、14例肺结核患者、16例矽肺患者以及15名无矽肺及其他伴随疾病的煤矿工人的血清血管紧张素转换酶(ACE)活性,以评估其作为这些疾病鉴别诊断的定向参数的有用性。我们发现,所有这些患者相对于对照组的值均显著升高:对照组(40.84±13.06 U/l),结节病(57.77±16.47 U/l),肺结核(46.85±10.25 U/l),矽肺(61.50±21.40 U/l),矿工(71.50±12.48 U/l)。除矿工和肺结核患者外,我们未检测到几个诊断组之间存在任何统计学上的显著差异(p = 0.04)。我们得出结论,该参数对于这些疾病的诊断定向不是非常有用。