Ichiyanagui C, Lozano R, Huamán C, Iparraguirre H
Hospital Nacional Daniel A. Carrión, Callao, Perú.
Rev Gastroenterol Peru. 1995 Jan-Apr;15(1):15-9.
This study was carried out at the of gastroenterology service from Hospital Nacional "Daniel A. Carrión" Callao-Peru, between June 1993 and May 1994, in order to determine the incidence, as well as, the clinical and endoscopic features of peptic ulcer disease in cirrhotic patients. 24 out of 46 (52.17%) hospitalized cirrhotic patient during this period, had peptic ulcer disease. The male:female ratio was 1:1. The mean age was 63.54 years, ranging from 44 to 90. There was statistical association (p < 0.05) between the severity of liver disease determined by Child Pugh Score and the presence of gastric ulcer. Regarding symptomatology, 54.16% had hematemesis and/or melena and 37.5% were asymptomatic. 6 patients had 2 or more ulcers, presenting the total series as a whole 35 ulcers, whose size ranged from 0.4 a 1.2 cm. Gastric antrum was the most often location (60%) followed by duodenal bulb (20%). We conclude that peptic ulcer disease in our cirrhotic patients is more frequent than reported by international literature (5-32%). Severity of liver disease was associated to gastric ulcer.
本研究于1993年6月至1994年5月在秘鲁卡亚俄市“丹尼尔·A·卡里翁国立医院”胃肠病科开展，旨在确定肝硬化患者消化性溃疡疾病的发病率以及临床和内镜特征。在此期间，46例住院肝硬化患者中有24例（52.17%）患有消化性溃疡疾病。男女比例为1:1。平均年龄为63.54岁，范围在44岁至90岁之间。根据Child Pugh评分确定的肝病严重程度与胃溃疡的存在之间存在统计学关联（p<0.05）。关于症状，54.16%的患者有呕血和/或黑便，37.5%的患者无症状。6例患者有2个或更多溃疡，整个系列共有35个溃疡，其大小在0.4至1.2厘米之间。胃窦是最常见的部位（60%），其次是十二指肠球部（20%）。我们得出结论，我们的肝硬化患者中消化性溃疡疾病比国际文献报道的更为常见（5%-32%）。肝病严重程度与胃溃疡有关。
