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针对因细菌性败血症导致呼吸衰竭的新生儿进行表面活性剂替代疗法。

Surfactant replacement therapy in neonates with respiratory failure due to bacterial sepsis.

作者信息

Fetter W P, Baerts W, Bos A P, van Lingen R A

机构信息

Department of Pediatrics, Sophia Hospital, Zwolle, The Netherlands.

出版信息

Acta Paediatr. 1995 Jan;84(1):14-6. doi: 10.1111/j.1651-2227.1995.tb13476.x.

DOI:10.1111/j.1651-2227.1995.tb13476.x
PMID:7734891
Abstract

We describe four newborns (gestational ages 29-37 weeks; birthweights 1380-3040 grams) who were mechanically ventilated for respiratory insufficiency because of bacterial sepsis. A beneficial effect of bovine surfactant (Alvofact, dosages 50 or 100 mg/kg) was found, as shown by decreases in mean airway pressures and oxygen demands. No side effects were seen after instillation.

摘要

我们描述了4名新生儿（胎龄29 - 37周；出生体重1380 - 3040克），他们因细菌性败血症导致呼吸功能不全而接受机械通气。结果发现牛肺表面活性剂（Alvofact，剂量为50或100毫克/千克）具有有益效果，表现为平均气道压力和氧气需求降低。滴注后未观察到副作用。

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Surfactant replacement therapy in neonates with respiratory failure due to bacterial sepsis.针对因细菌性败血症导致呼吸衰竭的新生儿进行表面活性剂替代疗法。
Acta Paediatr. 1995 Jan;84(1):14-6. doi: 10.1111/j.1651-2227.1995.tb13476.x.
2
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The effect of reconstituted bovine surfactant on pulmonary mechanics in infants with respiratory distress syndrome.重组牛肺表面活性物质对呼吸窘迫综合征婴儿肺力学的影响。
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Pediatrics. 1990 Nov;86(5):753-64.

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[Not Available].[无可用内容]
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