Eccles R
Common Cold and Nasal Research Centre, School of Molecular and Biomedical Sciences, University of Wales College of Cardiff, UK.
Eur Arch Otorhinolaryngol. 1995;252 Suppl 1:S2-7. doi: 10.1007/BF02484428.
The incidence of rhinitis is on the increase, especially in towns and cities with high levels of pollution from motor traffic and industry. There is a growing body of evidence which links this increased incidence of rhinitis to chronic nasal irritation from industrial pollution. Studies on the mechanisms of nasal inflammation and the nasal immune response are now providing insights into the etiology of rhinitis. This knowledge will help in the development of therapies aimed at alleviating the symptoms of rhinitis and controlling the development of rhinitis in susceptible individuals. This review discusses some of the factors that may explain the increased incidence of rhinitis and examines basic mechanisms involved in the nasal response to infection and allergy.
鼻炎的发病率正在上升，尤其是在机动车交通和工业污染程度高的城镇。越来越多的证据将鼻炎发病率的上升与工业污染导致的慢性鼻腔刺激联系起来。目前，关于鼻腔炎症机制和鼻腔免疫反应的研究正在为鼻炎的病因提供见解。这些知识将有助于开发旨在缓解鼻炎症状并控制易感个体鼻炎发展的治疗方法。这篇综述讨论了一些可能解释鼻炎发病率上升的因素，并研究了鼻腔对感染和过敏反应的基本机制。
