Trevino R J
Louisiana State University Medical Center, Shreveport, 95116, USA.
Otolaryngol Head Neck Surg. 1996 Feb;114(2):239-41. doi: 10.1016/S0194-59989670174-2.
The nose is the first organ system encountered by inhaled air and its associated pollutants. Pollutants are deposited during inspiration through the nose. They accumulate on mucus and are absorbed in the nasal mucosa, resulting in a number of deleterious effects on the body. Irritation of the nose and sinus from these pollutants, resulting from direct contact with the nasal mucosa, leads to inflammation, edema, swelling, and blocked sinuses. The result is acute and chronic sinusitis. Absorption of these chemicals into the body produces systemic effects. Their effect on the immune system, although subtle, leads to dramatic changes in the allergic diathesis. The T suppressor cell is the most sensitive cell of the immune system and the first to be affected by exposure to chemical pollutants. Diminution of the suppressor activity and the relative increase in helper activity in turn lead to increased immunoglobulin production and the manifestation of allergy symptoms. The underlying biochemical reaction is caused by the effects of pollutants on the T suppressor cell. Patients with existing allergies become brittle and difficult to treat with the exacerbation of the allergic diathesis. Removal of these chemical pollutants from the body as quickly as possible is essential for effective treatment of this problem. Dietary antioxidants help reduce the oxidizing effect of the pollutants and act as conjugators to remove the pollutants from the body.
鼻子是吸入空气及其相关污染物接触到的首个器官系统。污染物在吸气过程中通过鼻子沉积下来。它们积聚在黏液上，并被鼻黏膜吸收，从而对身体产生一系列有害影响。这些污染物直接接触鼻黏膜，会刺激鼻子和鼻窦，导致炎症、水肿、肿胀以及鼻窦堵塞。结果就是急慢性鼻窦炎。这些化学物质被人体吸收会产生全身影响。它们对免疫系统的影响虽然细微，但会导致过敏体质发生显著变化。T抑制细胞是免疫系统中最敏感的细胞，也是最先受到接触化学污染物影响的细胞。抑制活性的降低和辅助活性的相对增加反过来会导致免疫球蛋白产生增加以及过敏症状的显现。潜在的生化反应是由污染物对T抑制细胞的影响引起的。已有过敏症的患者会变得病情加重且难以治疗。尽快从体内清除这些化学污染物对于有效治疗该问题至关重要。膳食抗氧化剂有助于降低污染物的氧化作用，并作为结合剂将污染物从体内清除。
