Kubik A K, Parkin D M, Plesko I, Zatonski W, Kramarova E, Möhner M, Friedl H P, Juhasz L, Tzvetansky C G, Reissigova J
Institute of Chest Diseases, Prague, Czech Republic.
Cancer. 1995 May 15;75(10):2452-60. doi: 10.1002/1097-0142(19950515)75:10<2452::aid-cncr2820751010>3.0.co;2-e.
Remarkable increases in lung cancer risk recently have been observed in the Central and Eastern European (CEE) area. This study examines the patterns of lung cancer mortality rates and cigarette sales in 1960-1989 in seven CEE countries with a total population of 97.5 million and 43,000 deaths from lung cancer in the last year under study.
Trends in cigarette sales and mortality rates from lung cancer in seven CEE countries were compared for the years 1960-1989.
Among males, recent lung cancer death rates were the highest in Europe, and trends by country largely reflected the varied prevalence and duration of smoking in previous decades. For females, lung cancer mortality rates were much lower, although there were exponential rate increases. In the more recent birth cohorts, there were some declines in mortality rates among males, but not among females.
The rising cigarette consumption through the 1960s, 1970s, and, in some countries, the 1980s is accompanied in most of the countries by rising lung cancer mortality rates for young adults. This increasing cigarette consumption will determine future trends in lung cancer, which will increase well beyond the turn of the century and will continue longer for females than for males. This outlook underlines the urgent need for comprehensive lung cancer prevention with the concerted control of smoking as a priority. The role of cofactors and their interaction with smoking deserve further exploration.
最近在中欧和东欧(CEE)地区观察到肺癌风险显著增加。本研究调查了1960年至1989年期间七个中欧和东欧国家的肺癌死亡率模式和香烟销售量,这些国家总人口为9750万,在研究的最后一年有43000人死于肺癌。
比较了1960年至1989年期间七个中欧和东欧国家的香烟销售量趋势和肺癌死亡率趋势。
在男性中,近期肺癌死亡率在欧洲最高,各国的趋势在很大程度上反映了前几十年吸烟的不同流行程度和持续时间。对于女性来说,肺癌死亡率要低得多,尽管死亡率呈指数上升。在最近出生的队列中,男性的死亡率有所下降,但女性没有。
在20世纪60年代、70年代以及一些国家在80年代,香烟消费量不断上升,在大多数国家,这伴随着年轻人肺癌死亡率的上升。这种不断增加的香烟消费量将决定肺癌的未来趋势,肺癌死亡率在世纪之交后将大幅上升,女性持续的时间将比男性更长。这一前景凸显了迫切需要通过优先协同控制吸烟来进行全面的肺癌预防。辅助因素的作用及其与吸烟的相互作用值得进一步探索。