Rehůrek J, Snopková J
Dĕtská ocní klinika LF MU, Brno.
Cesk Slov Oftalmol. 1995 Feb;51(1):14-8.
The authors examined the lactic dehydrogenase activity and that of its isoenzymes in a group of 22 orbit with a confirmed diagnosis of retinoblastoma. They investigated and evaluate total LDH in the vitreous humour and blood serum and the ration of isoenzymes LDH 5 to LDH 1 in the same media. The assembled results confirmed that in eyes with retinoblastomas a significant pathological rise not only of the total LDH takes place but the response of isoenzymes is even more sensitive. The examination is therefore a qualitative asset to the clinical diagnosis of retinoblastoma.
作者检测了22例确诊为视网膜母细胞瘤的眼眶组织中的乳酸脱氢酶活性及其同工酶活性。他们研究并评估了玻璃体液和血清中的总乳酸脱氢酶，以及同一介质中乳酸脱氢酶5与乳酸脱氢酶1的比值。汇总结果证实，视网膜母细胞瘤患者的眼睛不仅总乳酸脱氢酶出现显著病理性升高，而且同工酶的反应更为敏感。因此，该检查对视网膜母细胞瘤的临床诊断具有重要价值。
