Kowalski W, Zwierzchowski H, Koktysz R
Katedry i Kliniki Ortopedii AM, łodzi.
Chir Narzadow Ruchu Ortop Pol. 1994;59(5):435-9.
Slow, symmetric epiphyseal distraction of the distal femur has been performed in 30 immature rabbits aged 10 weeks (group 1) and 16 weeks (group 2). Histological examination has been carried out after 2, 4, 12 and 24 weeks of distraction in both groups. In all animals hyperplasia and hypertrophy of the distracted epiphysis and regular remodeling of the bony growth zone were found after 4 weeks of follow-up. No premature closure of the physis has been noted compared to the controls. Histological differences observed were attributed to various, age related biological potential and they resulted from physiological involution.
对30只10周龄（第1组）和16周龄（第2组）的未成熟兔进行了股骨远端缓慢、对称的骨骺牵张。两组在牵张2、4、12和24周后进行了组织学检查。随访4周后，在所有动物中均发现牵张骨骺的增生和肥大以及骨生长区的正常重塑。与对照组相比，未发现骨骺过早闭合。观察到的组织学差异归因于各种与年龄相关的生物学潜能，它们是由生理退化引起的。
