Alberty A
Research Unit, Orthopaedic Hospital, Invalid Foundation, Helsinki, Finland.
J Pediatr Orthop. 1993 May-Jun;13(3):373-7. doi: 10.1097/01241398-199305000-00019.
To study the effects of physeal distraction on growth plate vascularity, microangiography was performed in 45 growing rabbits. Marked enlargement of the epiphyseal arteries and defective metaphyseal capillary filling were observed in association with hyperplasia and separation of the physes after 3 days of distraction, and the changes still persisted locally in specimens distracted for 21 days. New capillaries were observed in the hyperplastic physes and in separation gaps at 21 days. Vascular anastomoses across the physes were noted after 6 weeks of follow-up. Epiphyseal capillary enlargement may indicate increased nutritional demands of the physis, whereas metaphyseal changes are probably related to separation in the hypertrophic chondrocyte zone.
为研究骨骺牵张对生长板血管的影响,对45只生长中的兔子进行了微血管造影。牵张3天后,观察到骨骺动脉明显增粗,干骺端毛细血管充盈不良,同时伴有骨骺增生和分离,这些变化在牵张21天的标本中局部仍持续存在。在21天时,增生的骨骺和分离间隙中可见新生毛细血管。随访6周后,发现有跨越骨骺的血管吻合。骨骺毛细血管增粗可能表明骨骺对营养的需求增加,而干骺端的变化可能与肥大软骨细胞区的分离有关。