Sioutas C, Koutrakis P, Burton R M
Harvard University, School of Public Health, Boston, MA 02115, USA.
Environ Health Perspect. 1995 Feb;103(2):172-7. doi: 10.1289/ehp.95103172.
This paper presents the development and evaluation of an ambient particle concentrator for conducting animal inhalation exposure studies. The system utilizes the principle of virtual impactors to concentrate ambient particles in the size range 0.1-2.5 microns (aerodynamic diameter; dp) by drawing them through a series of three virtual impactors. Each impactor contains the majority of ambient fine mass (dp < 2.5 microns aerodynamic diameter) in a bleed flow (minor flow) that is 20% of the total flow entering the virtual impactor. The virtual impactors have been characterized using indoor air samples as test aerosols. Fine mass and sulfate concentrations at the outlet of the concentrating system were compared to the ambient fine mass and sulfate levels, which were determined using Harvard-Marple impactors. In each of the stages, particle concentration was increased by a factor of approximately 3. Thus, an overall concentration factor of about 25-30 was achieved. The main goal of this study was to demonstrate the feasibility of conducting animal exposures using the newly developed ambient fine particle concentrator.
本文介绍了一种用于进行动物吸入暴露研究的环境颗粒物浓缩器的开发与评估。该系统利用虚拟撞击器原理，通过一系列三个虚拟撞击器抽吸环境颗粒物，以浓缩粒径范围在0.1 - 2.5微米（空气动力学直径；dp）的颗粒物。每个撞击器将进入虚拟撞击器总流量20%的 bleed 流（次要流）中的大部分环境细颗粒物质量（空气动力学直径dp < 2.5微米）收集起来。已使用室内空气样本作为测试气溶胶对虚拟撞击器进行了表征。将浓缩系统出口处的细颗粒物质量和硫酸盐浓度与使用哈佛 - 马普尔撞击器测定的环境细颗粒物质量和硫酸盐水平进行了比较。在每个阶段，颗粒物浓度提高了约3倍。因此，实现了约25 - 30的总体浓缩系数。本研究的主要目标是证明使用新开发的环境细颗粒物浓缩器进行动物暴露的可行性。
