Boivin M J, Green S D, Davies A G, Giordani B, Mokili J K, Cutting W A
Department of Psychology, Spring Arbor College, Michigan 49283, USA.
Health Psychol. 1995 Jan;14(1):13-21. doi: 10.1037//0278-6133.14.1.13.
Fourteen asymptomatic HIV-infected Zairian children under 2 years of age displayed social and motor developmental deficits on the Denver Developmental Screening Test when compared with 20 HIV-negative cohorts born to HIV-infected mothers and 16 control children. In a second study, 11 infected children over 2 years of age had sequential motor and visual-spatial memory deficits on the Kaufman Assessment Battery for Children and motor development deficits on the Early Childhood Screening Profiles. HIV infection affects central nervous system structures mediating motor and spatial memory development, even in seemingly asymptomatic children. Furthermore, maternal HIV infection compromises the labor-intensive provision of care in the African milieu and undermines global cognitive development in even uninfected children.
与20名感染艾滋病毒母亲所生的艾滋病毒阴性儿童以及16名对照儿童相比，14名2岁以下无症状感染艾滋病毒的扎伊尔儿童在丹佛发育筛查测试中表现出社交和运动发育缺陷。在第二项研究中，11名2岁以上的受感染儿童在考夫曼儿童能力评估测验中出现了连续的运动和视觉空间记忆缺陷，在幼儿筛查量表中出现了运动发育缺陷。艾滋病毒感染会影响介导运动和空间记忆发育的中枢神经系统结构，即使在看似无症状的儿童中也是如此。此外，母亲感染艾滋病毒会影响非洲环境中需要大量人力的护理工作，甚至会损害未感染儿童的整体认知发育。
