Lynch J W, Bailey J W
Department of Nutrition, College of Human Ecology and Agricultural Experiment Station, University of Tennessee, Knoxville 37996-1900, USA.
J Nutr. 1995 May;125(5):1267-73. doi: 10.1093/jn/125.5.1267.
Diets containing either triacetin (the water-soluble triglyceride of acetate) or long-chain triglycerides (LCT) were fed to rats for 30 d to determine the effect on body weight gain and adipose tissue cellularity. Male Sprague-Dawley rats were allowed free access to one of three diets: a control diet containing 5% of energy as fat or one of two experimental diets that contained 30% triglyceride (by energy). The source of the triglyceride in the two experimental groups was either 100% LCT or 95% triacetin + 5% LCT. Within the experimental groups receiving 30% fat, the source of dietary triglyceride (LCT vs. triacetin) did not affect total energy consumption. There were no significant differences in body weight at the onset of the study; however, animals fed 100% LCT weighed significantly more than the other two groups at the end of the study. In all three fat pads studied, animals fed triacetin had significantly lower pad mass than did animals fed LCT. Mean fat cell size was smaller in fat depots of animals fed short-chain triglyceride. Provision of dietary energy as the short-chain triglyceride triacetin in lieu of LCT resulted in lower weight gain and fat deposition. These data demonstrate the impact of dietary triglyceride composition on body weight regulation.
给大鼠喂食含有三醋精（醋酸的水溶性甘油三酯）或长链甘油三酯（LCT）的饮食30天，以确定其对体重增加和脂肪组织细胞构成的影响。雄性斯普拉格-道利大鼠可以自由选择三种饮食中的一种：一种对照饮食，其脂肪提供5%的能量；或者两种实验饮食中的一种，这两种实验饮食含有30%的甘油三酯（按能量计算）。两个实验组中甘油三酯的来源要么是100%的LCT，要么是95%的三醋精+5%的LCT。在接受30%脂肪的实验组中，饮食中甘油三酯的来源（LCT与三醋精）不影响总能量消耗。研究开始时体重没有显著差异；然而，在研究结束时，喂食100%LCT的动物体重明显高于其他两组。在研究的所有三个脂肪垫中，喂食三醋精的动物的脂肪垫质量明显低于喂食LCT的动物。喂食短链甘油三酯的动物脂肪库中的平均脂肪细胞大小较小。用短链甘油三酯三醋精代替LCT提供饮食能量会导致体重增加和脂肪沉积减少。这些数据证明了饮食中甘油三酯组成对体重调节的影响。
