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老年患者胆总管残留结石胆道支架的长期随访

Longterm follow-up of biliary stents for retained common bile duct stones in elderly patients.

作者信息

Lauri A, Davidson B R, Horton R, Burroughs A, Dooley J S

机构信息

Hepatobiliary and Liver Transplantation Unit, Royal Free Hospital and School of Medicine, London, UK.

出版信息

J R Coll Surg Edinb. 1995 Feb;40(1):42-5.

PMID:7738897
Abstract

Common bile duct (CBD) stones in elderly patients are best treated by endoscopic sphincterotomy (ES). If CBD clearance cannot be achieved endoscopically a biliary stent may be inserted. Although satisfactory short-term results have been reported, few reports on their longterm outcome are available. Over a 3-year period, January 1987 to December 1989, 100 patients with CBD stones were referred for endoscopic stone removal. In 14 of these patients (3 men, 11 women; median age 83 years, range 79-97 years) the CBD could not be cleared endoscopically and a stent was inserted. Twelve of the 14 patients were jaundiced and 5 had acute cholangitis (AC). The maximum diameter of the retained stones ranged from 10-42 mm with a median of 17 mm. Stent insertion resolved jaundice and sepsis in all cases and all patients were discharged from hospital. In-patient stay ranged from 1-82 days (median 12 days) and was significantly increased by the presence of acute cholangitis (P = 0.03, Mann-Whitney U-test). Longterm follow-up was obtained in 13 of the 14 patients (93%) by referral to their general practitioner and out-patient notes. Seven patients are alive and well (median follow-up 43 months, range 34-60 months). One of these 7 developed further jaundice owing to stent migration and had further ES and stone removal. Six patients died at 1, 3, 12, 32, 36 and 42 months following stent insertion from unrelated causes. One patient developed further AC requiring antibiotic treatment and another patient required stent replacement.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

老年患者的胆总管结石最好通过内镜括约肌切开术(ES)进行治疗。如果内镜下无法实现胆总管结石清除,可插入胆管支架。尽管已有关于其短期效果令人满意的报道,但关于其长期结果的报道却很少。在1987年1月至1989年12月的3年期间,100例胆总管结石患者被转诊接受内镜下取石治疗。其中14例患者(3例男性,11例女性;年龄中位数83岁,范围79 - 97岁)内镜下无法清除胆总管结石,遂插入了支架。14例患者中有12例出现黄疸,5例发生急性胆管炎(AC)。残留结石的最大直径为10 - 42毫米,中位数为17毫米。支架置入术在所有病例中均消除了黄疸和脓毒症,所有患者均出院。住院时间为1 - 82天(中位数12天),急性胆管炎的存在显著延长了住院时间(P = 0.03,曼 - 惠特尼U检验)。通过转诊至其全科医生和门诊病历,对14例患者中的13例(93%)进行了长期随访。7例患者存活且状况良好(随访中位数43个月,范围34 - 60个月)。这7例患者中有1例因支架移位再次出现黄疸,接受了进一步的内镜括约肌切开术和结石清除术。6例患者在支架置入后1、3、12、32、36和42个月因无关原因死亡。1例患者再次发生急性胆管炎,需要抗生素治疗,另1例患者需要更换支架。(摘要截短至250字)

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