Davidson B R, Lauri A, Horton R, Burroughs A, Dooley J
Hepatobiliary and Liver Transplantation Unit, Royal Free Hospital and Medical School, London.
Ann R Coll Surg Engl. 1994 Sep;76(5):320-3.
Endoscopic sphincterotomy (ES) is the treatment of choice for common bile duct stones in elderly patients. For those in whom endoscopic clearance of the common bile duct fails the treatment options include stenting, dissolution therapy and lithotripsy. Surgery is often avoided because of the reported high morbidity and mortality in elderly patients. We have reviewed the outcome of patients referred for surgery after failed endoscopic clearance of common bile duct stones. Over a 3-year period, 100 patients with common bile duct stones were referred specifically for endoscopic clearance of the common bile duct (median age 69 years, range 19-97 years). In seven patients duct clearance was possible without ES and in five patients ES was considered inappropriate. ES was attempted in 88 patients and was successful in 75 (85%). Of the 13 patients failing ES or stone removal, surgery was performed in nine and four were stented. Of patients having successful ES (n = 75), ten were referred for surgery because of incomplete duct clearance. Surgery was performed to obtain duct clearance in 19 patients (eight male, 11 female, median age 77 years, range 47-90 years). Of the 19, eight had previously undergone a cholecystectomy (42%) and 17 of the 19 had biliary tract drainage preoperatively (90%). The procedures performed consisted of choledocholithotomy in all plus cholecystectomy (11), choledochoduodenostomy (7) and choledochojejunostomy (7). There were no deaths and only one major complication. The median total inpatient stay was 26 days (range 14-75 days) and the median postoperative stay was 12 days (range 7-50 days). We would conclude that open surgery can be performed safely and effectively in elderly patients with retained bile duct stones.
内镜括约肌切开术(ES)是老年患者胆总管结石的首选治疗方法。对于那些内镜下胆总管结石清除失败的患者,治疗选择包括支架置入、溶石疗法和碎石术。由于报道老年患者手术的发病率和死亡率较高,通常避免手术治疗。我们回顾了内镜下胆总管结石清除失败后转诊手术患者的治疗结果。在3年期间,100例胆总管结石患者专门转诊接受内镜下胆总管结石清除术(中位年龄69岁,范围19 - 97岁)。7例患者无需ES即可清除胆管结石,5例患者认为不适合行ES。88例患者尝试行ES,75例成功(85%)。在13例ES或结石清除失败的患者中,9例行手术治疗,4例行支架置入。在ES成功的患者(n = 75)中,10例因胆管清除不完全而转诊手术。19例患者(8例男性,11例女性,中位年龄77岁,范围47 - 90岁)行手术以清除胆管结石。19例患者中,8例曾行胆囊切除术(42%),19例中有17例术前进行了胆道引流(90%)。所进行的手术包括全部患者的胆总管切开取石术,以及胆囊切除术(11例)、胆总管十二指肠吻合术(7例)和胆总管空肠吻合术(7例)。无死亡病例,仅1例严重并发症。总住院时间中位数为26天(范围14 - 75天),术后住院时间中位数为12天(范围7 - 50天)。我们得出结论,对于残留胆管结石的老年患者,开放手术可以安全有效地进行。