Demikhov V G, Chaĭtsev V G
Vopr Virusol. 1995 Jan-Feb;40(1):21-5.
Two principal forms of diseases caused by Inkoo and Tahyna viruses were observed, fever (25 pts, 61%) and neuroinfection (13 pts, 31.7%). In 3 (7.3%) subjects the infection was inapparent. Ten patients presented with mixed forms of infection (virus-virus or virus-bacterial). Clinical manifestations were characterized by marked polymorphism and low specificity. The onset was acute with expressed symptoms of infection and weak catarrhal manifestations. Of the patients with the neuroinfectious form of the disease 3 presented with aseptic meningitis, 2 with meningoencephalitis, and 5 with encephalitis. Aseptic meningitis was characterized by a combination of general infectious and moderately expressed meningeal syndromes with weak inflammatory changes in the spinal fluid. Encephalitides were associated with numerous neurological symptoms which manifested on days 3-7 of the illness. These symptoms were asymmetry of nasolabial folds, hemiparesis, dysarthria, dysphagia, generalized tremor, tongue deviation. No significant differences in the clinical manifestations of Inkoo and Tahyna infections were observed.
观察到因印古病毒和塔希纳病毒引起的两种主要疾病形式,即发热(25例,61%)和神经感染(13例,31.7%)。3例(7.3%)患者感染不明显。10例患者表现为混合感染形式(病毒-病毒或病毒-细菌)。临床表现具有显著的多态性且特异性较低。起病急,有明显的感染症状且卡他症状轻微。在患有神经感染型疾病的患者中,3例表现为无菌性脑膜炎,2例为脑膜脑炎,5例为脑炎。无菌性脑膜炎的特征是一般感染症状与中度明显的脑膜综合征相结合,脑脊液炎症变化轻微。脑炎伴有多种神经症状,在疾病第3 - 7天出现。这些症状包括鼻唇沟不对称、偏瘫、构音障碍、吞咽困难、全身性震颤、舌偏斜。未观察到印古病毒和塔希纳病毒感染在临床表现上的显著差异。