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主动脉瓣置换术和冠状动脉搭桥术后使用心室辅助泵成功治疗右心室衰竭。

Successful management of right ventricular failure with the ventricular assist pump following aortic valve replacement and coronary bypass grafting.

作者信息

O'Neill M J, Pierce W S, Wisman C B, Osbakken M D, Parr G V, Waldhausen J A

出版信息

J Thorac Cardiovasc Surg. 1984 Jan;87(1):106-11.

PMID:6690848
Abstract

Right ventricular failure is an infrequent but potentially lethal complication of cardiac surgical procedures. We have successfully treated a patient with right ventricular failure with the use of a right ventricular assist pump (RVAP). This patient had aortic stenosis and coronary artery disease involving the circumflex and right coronary arteries. He also had chronic obstructive pulmonary disease with mild pulmonary hypertension (mean pulmonary artery pressure of 26 mm Hg) and evidence of mild right ventricular failure (right ventricular pressure of 40/14 mm Hg). Gated radionuclide angiography, performed preoperatively, showed that the right ventricle had normal wall motion. Right ventricular failure prevented discontinuation of cardiopulmonary bypass despite use of an intra-aortic balloon pump. The right atrial pressure was 20 mm Hg with a left atrial pressure of 8 to 10 mm Hg. Bypass was readily discontinued following implantation of the RVAP. Recovery of the patient's right ventricle was evaluated with serial determinations of right ventricular work. The RVAP was removed on the fifth postoperative day and the patient made a complete recovery. Postoperatively, gated radionuclide angiography demonstrated moderate recovery of right ventricular function. We suspect that the perioperative right ventricular failure was a result of unsatisfactory myocardial protection due to total occlusion of the proximal right coronary artery, which resulted in a maldistribution of the cardioplegic solution. This case demonstrates that right ventricular function can be restored following circulatory support with a mechanical assist device.

摘要

右心室衰竭是心脏外科手术中一种少见但可能致命的并发症。我们使用右心室辅助泵(RVAP)成功治疗了一名右心室衰竭患者。该患者患有主动脉瓣狭窄以及累及回旋支和右冠状动脉的冠状动脉疾病。他还患有慢性阻塞性肺疾病,伴有轻度肺动脉高压(平均肺动脉压为26 mmHg)以及轻度右心室衰竭的证据(右心室压力为40/14 mmHg)。术前进行的门控放射性核素血管造影显示右心室壁运动正常。尽管使用了主动脉内球囊泵,但右心室衰竭仍导致体外循环无法撤离。右心房压力为20 mmHg,左心房压力为8至10 mmHg。植入RVAP后,体外循环很容易就撤离了。通过连续测定右心室做功来评估患者右心室的恢复情况。术后第5天移除了RVAP,患者完全康复。术后,门控放射性核素血管造影显示右心室功能有中度恢复。我们怀疑围手术期右心室衰竭是由于右冠状动脉近端完全闭塞导致心肌保护不充分,进而引起心脏停搏液分布不均所致。该病例表明,使用机械辅助装置进行循环支持后,右心室功能可以恢复。

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