Loesche W J
School of Medicine, University of Michigan, Ann Arbor.
Compendium. 1994 Aug;15(8):976, 978-82, 985-6 passim; quiz 992.
Many individuals with cardiovascular disease appear from epidemiologic studies to have either periodontal disease or to be edentulous. A Finnish group has provided evidence that after conventional risk factors for stroke and heart attacks have been accounted for, there still remains a significant relationship between dental disease and cardiovascular disease. A preliminary analysis of our own investigation of the interrelationship of medical and dental health shows that individuals with a high dental morbidity (ie, edentulous or with many missing teeth) have a high prevalence of coronary heart disease and stroke. A model based on how smoking can predispose to periodontal disease is used to explain how periodontal disease could be a potential risk factor for heart disease.
许多患有心血管疾病的个体从流行病学研究来看，要么患有牙周疾病，要么无牙。一个芬兰研究小组已提供证据表明，在考虑了中风和心脏病的传统风险因素之后，牙齿疾病与心血管疾病之间仍存在显著关联。我们自己对医疗与牙齿健康相互关系的调查初步分析表明，牙齿发病率高（即无牙或有许多牙齿缺失）的个体冠心病和中风的患病率也高。一个基于吸烟如何易患牙周疾病的模型被用来解释牙周疾病如何可能成为心脏病的一个潜在风险因素。
