Dill S R, Cobbs C G, McDonald C K
Division of Infectious Diseases, University of South Alabama Medical Center, Mobile, USA.
Clin Infect Dis. 1995 Feb;20(2):372-86. doi: 10.1093/clinids/20.2.372.
Thirty-two patients with subdural empyema at the University Hospital (Birmingham, AL) during the period from June 1970 through June 1992 were identified retrospectively. Clinical presentations of patients, methods of diagnosis, results of microbiological tests, types of therapy used, and outcomes of patients are presented and compared with those found in prior reports. The patients were separated into three groups based on the etiology of their disease: sinusitis, trauma and/or neurosurgery, and other miscellaneous causes. Sinusitis accounted for 56% of the cases; the predominant organisms isolated from these patients were anaerobes and streptococci. No cases occurred secondary to otitis media. The overall mortality rate was 9%; however, 55% of patients had neurological deficiency at the time they were discharged from the hospital. Factors that affected survival were age (P < .007) and level of consciousness at presentation (P < .008).
对1970年6月至1992年6月期间在阿拉巴马大学伯明翰分校医院收治的32例硬膜下积脓患者进行了回顾性研究。文中介绍了患者的临床表现、诊断方法、微生物检测结果、所采用的治疗类型以及患者的治疗结果，并与既往报道进行了比较。根据病因将患者分为三组：鼻窦炎、创伤和/或神经外科手术以及其他杂类病因。鼻窦炎占病例的56%；从这些患者中分离出的主要病原体是厌氧菌和链球菌。无中耳炎继发病例。总死亡率为9%；然而，55%的患者出院时存在神经功能缺损。影响生存的因素为年龄（P < 0.007）和就诊时的意识水平（P < 0.008）。
